The MED19 Polyclonal Antibody (CAB17844) is a valuable tool for researchers studying the MED19 protein, a key component of the mediator complex involved in transcription regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the MED19 protein, this antibody allows for the detection and analysis of MED19 in various cell types, making it ideal for investigations in molecular biology and gene expression studies.MED19 plays a crucial role in facilitating transcription by promoting the recruitment of RNA polymerase II to gene promoters. Its involvement in regulating gene expression makes it a target of interest for researchers studying various cellular processes, including development, differentiation, and disease pathogenesis.
Understanding the function of MED19 is essential for unraveling the mechanisms underlying these biological processes and identifying potential therapeutic targets for a range of diseases.Overall, the MED19 Polyclonal Antibody (CAB17844) provides a reliable tool for researchers seeking to explore the role of MED19 in gene regulation and transcriptional control. Its specificity and sensitivity make it a valuable asset in the study of molecular mechanisms driving cellular function and disease progression.
Product Name:
MED19 Rabbit Polyclonal Antibody
SKU:
CAB17844
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-160 of human MED19 (NP_703151.1).
The protein encoded by this gene is a subunit of the Mediator complex, which binds to gene-specific regulatory factors and provides support for the basal RNA polymerase II transcription machinery. This gene has been implicated in the growth of several types of cancer, and inhibition of its expression inhibits the growth and spread of these cancers. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
219541
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MED19 Rabbit pAb (CAB17844) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
