MED17 Rabbit Polyclonal Antibody (CAB8716)
- SKU:
- CAB8716
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | MED17 Rabbit Polyclonal Antibody |
SKU: | CAB8716 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 250-460 of human MED17 (NP_004259.3). |
Sequence: | DLEG SAYI KVSI QKQA PDIG DLGT VNLF KRPL PKSK PGSP HWQT KLEA AQNV LLCK EIFA QLSR EAVQ IKSQ VPHI VVKN QIIS QPFP SLQL SISL CHSS NDKK SQKF ATEK QCPE DHLY VLEH NLHL LIRE FHKQ TLSS IMMP HPAS APFG HKRM RLSG PQAF DKNE INSL QSSE GLLE KIIK QAKH IFLR SRAA ATID SLAS RIED PQI |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | SRB4; CRSP6; CRSP77; DRIP80; TRAP80; MED17 |
Positive Sample: | HeLa,293T,A-431,Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 73kDa |
Observed MW: | 80kDa |
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Purification Method: | Affinity purification |
Gene ID: | 9440 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |