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MECR Antibody (PACO10436)

SKU:
PACO10436
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459
Frequently bought together:

Description

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MECR Antibody (PACO10436)

The MECR Polyclonal Antibody (PAC010436) is a valuable tool for researchers studying MECR, a key enzyme involved in mitochondrial fatty acid biosynthesis. This antibody, generated in rabbits, exhibits high specificity and sensitivity when used in various immunoassays such as Western blotting. It specifically recognizes the MECR protein, enabling researchers to detect and study its expression levels in different cell types.MECR is essential for the production of long-chain fatty acids in mitochondria, playing a crucial role in energy metabolism and lipid biosynthesis.

Dysregulation of MECR is associated with metabolic disorders and cancer, making it an important target for therapeutic interventions. By studying the function of MECR using this antibody, researchers can gain valuable insights into potential treatment strategies for these diseases.Overall, the MECR Polyclonal Antibody is a valuable tool for researchers investigating the role of MECR in metabolic pathways and disease development. Its high reactivity and specificity make it a reliable choice for studies in biochemistry, cell biology, and molecular biology.

Antibody Name:MECR Antibody (PACO10436)
Antibody SKU:PACO10436
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human MECR
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:mitochondrial trans-2-enoyl-CoA reductase;MECR;CGI-63;FASN2B;NRBF1 ;
UniProt Protein Function:MECR: Catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. May have a role in the mitochondrial synthesis of fatty acids. Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Lipid Metabolism - fatty acid elongation in mitochondria; Oxidoreductase; EC 1.3.1.38

Chromosomal Location of Human Ortholog: 1p35.3

Cellular Component: mitochondrion; nucleus

Molecular Function:zinc ion binding; trans-2-enoyl-CoA reductase (NADPH) activity

Biological Process: fatty acid metabolic process; fatty acid biosynthetic process

UniProt Code:Q9BV79
NCBI GenInfo Identifier:334302832
NCBI Gene ID:51102
NCBI Accession:Q9BV79.2
UniProt Secondary Accession:Q9BV79,Q5SYU0, Q5SYU1, Q5SYU2, Q6IBU9, Q9Y373, B3KT72
UniProt Related Accession:Q9BV79
Molecular Weight:373
NCBI Full Name:Trans-2-enoyl-CoA reductase, mitochondrial
NCBI Synonym Full Names:mitochondrial trans-2-enoyl-CoA reductase
NCBI Official Symbol:MECR  
NCBI Official Synonym Symbols:NRBF1; CGI-63; FASN2B  
NCBI Protein Information:trans-2-enoyl-CoA reductase, mitochondrial; nuclear receptor binding factor 1; mitochondrial 2-enoyl thioester reductase; homolog of yeast 2-enoyl thioester reductase
UniProt Protein Name:Trans-2-enoyl-CoA reductase, mitochondrial
UniProt Synonym Protein Names:Nuclear receptor-binding factor 1; HsNrbf-1; NRBF-1
UniProt Gene Name:MECR  
UniProt Entry Name:MECR_HUMAN

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