MECOM Rabbit Polyclonal Antibody (CAB5674)
- SKU:
- CAB5674
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MECOM Rabbit Polyclonal Antibody |
SKU: | CAB5674 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human MECOM (NP_004982.2). |
Sequence: | MRSK GRAR KLAT NNEC VYGN YPEI PLEE MPDA DGVA STPS LNIQ EPCS PATS SEAF TPKE GSPY KAPI YIPD DIPI PAEF ELRE SNMP GAGL GIWT KRKI EVGE KFGP YVGE QRSN LKDP SYGW EILD EFYN VKFC IDAS QPDV GSWL KYIR FAGC YDQH NLVA CQIN DQIF YRVV ADIA PGEE LLLF MK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | EVI1; MDS1; KMT8E; PRDM3; RUSAT2; MDS1-EVI1; AML1-EVI-1; MECOM |
Positive Sample: | SKOV3,HL-60(Negative control),Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus, Nucleus speckle. |
Calculated MW: | 18kDa/117kDa/118kDa/125kDa/139kDa |
Observed MW: | 105kDa/145kDa |
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 2122 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |