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MDR1 Antibody (PACO34138)

SKU:
PACO34138
Product Type:
Antibody
Reactivity:
Plasmodium
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
$407
Frequently bought together:

Description

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MDR1 Antibody (PACO34138)

The MDR1 Antibody (PAC034138) is a high-quality polyclonal antibody designed for research involving the MDR1 protein, also known as P-glycoprotein. This cell surface molecule is a key player in multidrug resistance in cancer cells, playing a role in efflux pump activity that reduces the efficacy of chemotherapy drugs.Raised in rabbits, this antibody is highly specific and reactive with human samples, making it ideal for use in Western blotting and immunohistochemistry applications. It binds to the MDR1 protein, enabling accurate detection and analysis in various cell types, particularly in studies related to cancer research and drug resistance mechanisms.

Understanding the function of MDR1 is critical for developing strategies to overcome multidrug resistance in cancer treatment. By targeting this protein, researchers can investigate novel approaches to enhance drug delivery and efficacy, ultimately improving outcomes for cancer patients. The MDR1 Antibody offers a reliable tool for studying the mechanisms underlying drug resistance and developing innovative therapeutic interventions.

Antibody Name:MDR1 Antibody (PACO34138)
Antibody SKU:PACO34138
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA
Recommended Dilutions:
Species Reactivity:Plasmodium falciparum
Immunogen:Recombinant Plasmodium falciparum Multidrug resistance protein (1084-1419AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Background:Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
Synonyms:Multidrug resistance protein (EC 3.6.3.44) (Chloroquine resistance protein), MDR1
UniProt Protein Function:Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
UniProt Protein Details:
NCBI Summary:
UniProt Code:P13568
NCBI GenInfo Identifier:126936
NCBI Gene ID:
NCBI Accession:P13568.1
UniProt Secondary Accession:P13568
UniProt Related Accession:P13568
Molecular Weight:54.17kD
NCBI Full Name:Multidrug resistance protein
NCBI Synonym Full Names:
NCBI Official Symbol:
NCBI Official Synonym Symbols:
NCBI Protein Information:
UniProt Protein Name:Multidrug resistance protein
UniProt Synonym Protein Names:Chloroquine resistance protein
Protein Family:Multidrug resistance protein
UniProt Gene Name:MDR1  
UniProt Entry Name:

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