The MDM1 Polyclonal Antibody (PAC010431) is a valuable tool for researchers studying MDM1, a protein involved in various cellular processes, including cell growth and division. This antibody, produced in rabbits, exhibits strong reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the MDM1 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it well-suited for research in molecular biology and cancer biology.MDM1, also known as melastatin, plays a crucial role in regulating cell proliferation and apoptosis, making it a potential target for cancer therapy.
Its involvement in cell cycle progression and DNA damage response underscores its importance in maintaining cellular homeostasis and genomic stability. Investigating the function of MDM1 can provide insights into cancer development and progression, guiding the development of novel treatment strategies.Overall, the MDM1 Polyclonal Antibody is a reliable tool for researchers interested in exploring the roles of MDM1 in cellular physiology and disease pathology. Its high specificity and sensitivity make it a valuable asset for studies in cancer research and drug development.
Mdm1 nuclear protein homolog (mouse);MDM1;FLJ95264 ;
UniProt Protein Function:
MDM1: a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles, is amplified in the mouse transformed 3T3 cell line, and the encoded protein is able to bind to p53. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]Protein type: Unknown functionChromosomal Location of Human Ortholog: 12q15Cellular Component: centriole; centrosome; nucleusMolecular Function: microtubule bindingBiological Process: negative regulation of centriole replication; retina development in camera-type eye
UniProt Protein Details:
NCBI Summary:
This gene encodes a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles, is amplified in the mouse transformed 3T3 cell line, and the encoded protein is able to bind to p53. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
