The MDGA2 Polyclonal Antibody (CAB14969) is a vital tool for researchers studying MDGA2, a cell adhesion molecule that plays a crucial role in neural development and synaptic function. This antibody, produced in rabbits, exhibits high specificity and sensitivity for human samples and is validated for use in various applications, including Western blot analysis.MDGA2, also known as MAM domain-containing glycosylphosphatidylinositol anchor protein 2, is essential for proper brain development and function, regulating synaptic connectivity and plasticity. Dysfunction of MDGA2 has been linked to neurodevelopmental disorders and neurological conditions, making it a key target for research in neuroscience and neurobiology.
By utilizing the MDGA2 Polyclonal Antibody, researchers can detect and analyze MDGA2 expression in different cell types and tissues, providing important insights into its role in neural development and function. This antibody is invaluable for studies investigating the mechanisms underlying neurological disorders and potential therapeutic interventions aimed at addressing these conditions.
Product Name:
MDGA2 Rabbit Polyclonal Antibody
SKU:
CAB14969
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 620-820 of human MDGA2 (NP_001106970.3).
Predicted to be involved in regulation of presynapse assembly; regulation of synaptic membrane adhesion; and spinal cord motor neuron differentiation. Predicted to act upstream of or within neuron migration and pattern specification process. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in GABA-ergic synapse and glutamatergic synapse.
Purification Method:
Affinity purification
Gene ID:
161357
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MDGA2 Rabbit pAb (CAB14969) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
