The MDFI Polyclonal Antibody (CAB13709) is a vital tool for researchers studying MDFI, a key regulator of gene expression with implications in various biological processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the MDFI protein, researchers can accurately detect and analyze its expression in a wide range of cell types, making this antibody essential for studies in molecular biology and gene regulation.MDFI, also known as MyoD family inhibitor, is a critical transcriptional regulator involved in modulating the activity of MyoD family proteins, which play essential roles in muscle differentiation and development.
Understanding the function of MDFI is crucial for unraveling the complex mechanisms underlying gene expression and cellular differentiation. Research on MDFI has implications for various fields, including developmental biology, regenerative medicine, and disease pathology.Overall, the MDFI Polyclonal Antibody (CAB13709) is a valuable tool for researchers looking to delve deeper into the role of MDFI in gene regulation and cellular processes. Its high specificity and sensitivity make it an ideal choice for studies aiming to unravel the intricate mechanisms of gene expression and regulation in both normal and pathological conditions.
Product Name:
MDFI Rabbit Polyclonal Antibody
SKU:
CAB13709
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human MDFI (NP_005577.1).
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.
Purification Method:
Affinity purification
Gene ID:
4188
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MDFI Rabbit pAb (CAB13709) at 1:3000 dilution.
