UniProt Protein Function: | Mcpt4: Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-|-Ile-5' bond of angiotensin I and the 'Phe-20-|-Ala-21' bond of amyloid beta- protein, and is less active towards the 'Phe-8-|-His-9' bond of angiotensin I and the 'Phe-4-|-Ala-5' and 'Tyr-10-|-Glu-11' bonds of amyloid beta-protein. Involved in thrombin regulation and fibronectin processing. Belongs to the peptidase S1 family. Granzyme subfamily.Protein type: EC 3.4.21.-; ProteaseCellular Component: cytoplasm; intracellular; intracellular membrane-bound organelleMolecular Function: hydrolase activity; peptidase activity; serine-type endopeptidase activity; serine-type peptidase activityBiological Process: immune response; protein processing; proteolysis; regulation of angiotensin levels in blood |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | P21812 |
NCBI GenInfo Identifier: | 114205406 |
NCBI Gene ID: | 17227 |
NCBI Accession: | NP_034909.2 |
UniProt Secondary Accession: | P21812,Q9EPQ9, Q9EQT2 |
UniProt Related Accession: | P21812 |
Molecular Weight: | 27,204 Da |
NCBI Full Name: | mast cell protease 4 |
NCBI Synonym Full Names: | mast cell protease 4 |
NCBI Official Symbol: | Mcpt4Â Â |
NCBI Official Synonym Symbols: | Mcp4; Mcp-4; MMCP-4; MMCP-4A; MMCP-4BÂ Â |
NCBI Protein Information: | mast cell protease 4 |
UniProt Protein Name: | Mast cell protease 4 |
UniProt Synonym Protein Names: | MSMCP; Myonase; Serosal mast cell protease |
Protein Family: | Mast cell protease |
UniProt Gene Name: | Mcpt4Â Â |
UniProt Entry Name: | MCPT4_MOUSE |