The MCPT4 Polyclonal Antibody (PACO34310) is an essential tool for researchers studying the mast cell-specific protease MCPT4, which plays a key role in various immune responses such as inflammation and allergic reactions. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.MCPT4 is a protease enzyme that is primarily expressed in mast cells and is involved in the regulation of immune responses, particularly in the context of allergic reactions and inflammatory processes.
By specifically targeting MCPT4, researchers can gain insights into its function and role in various diseases such as asthma, allergic rhinitis, and other allergic disorders.This antibody enables the detection and analysis of MCPT4 in different cell types, making it a valuable tool for immunology and allergy research. Understanding the mechanisms of MCPT4 can lead to the development of targeted therapies for managing immune-related conditions and designing strategies to modulate immune responses effectively.
Antibody Name:
Mcpt4 Antibody (PACO34310)
Antibody SKU:
PACO34310
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Mouse
Immunogen:
Recombinant Mouse Mast cell protease 4 protein (21-246AA)
Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4- |-Ile-5' bond of angiotensin I and the 'Phe-20- |-Ala-21' bond of amyloid beta-protein, and is less active towards the 'Phe-8- |-His-9' bond of angiotensin I and the 'Phe-4- |-Ala-5' and 'Tyr-10- |-Glu-11' bonds of amyloid beta-protein. Involved in thrombin regulation and fibronectin processing.
Mcpt4: Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-|-Ile-5' bond of angiotensin I and the 'Phe-20-|-Ala-21' bond of amyloid beta- protein, and is less active towards the 'Phe-8-|-His-9' bond of angiotensin I and the 'Phe-4-|-Ala-5' and 'Tyr-10-|-Glu-11' bonds of amyloid beta-protein. Involved in thrombin regulation and fibronectin processing. Belongs to the peptidase S1 family. Granzyme subfamily.Protein type: EC 3.4.21.-; ProteaseCellular Component: cytoplasm; intracellular; intracellular membrane-bound organelleMolecular Function: hydrolase activity; peptidase activity; serine-type endopeptidase activity; serine-type peptidase activityBiological Process: immune response; protein processing; proteolysis; regulation of angiotensin levels in blood
