MCOLN2 Rabbit Polyclonal Antibody (CAB18560)
- SKU:
- CAB18560
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MCOLN2 Rabbit Polyclonal Antibody |
SKU: | CAB18560 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 90-275 of human MCOLN2 (NP_694991.2). |
Sequence: | VVAF KEDN TVAF KHLF LKGY SGTD EDDY SCSV YTQE DAYE SIFF AINQ YHQL KDIT LGTL GYGE NEDN RIGL KVCK QHYK KGTM FPSN ETLN IDND VELD CVQL DLQD LSKK PPDW KNSS FFRL EFYR LLQV EISF HLKG IDLQ TIHS RELP DCYV FQNT IIFD NKAH SGKI KIYF DSDA KIEE CK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | TRPML2; TRP-ML2; MCOLN2 |
Positive Sample: | THP-1,SKOV3 |
Cellular Localization: | lysosome, plasma membrane |
Calculated MW: | 66kDa |
Observed MW: | 75kDa |
Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals, the mucolipin family includes 3 members, MCOLN1 (MIM 605248), MCOLN2, and MCOLN3 (MIM 607400), that exhibit a common 6-membrane-spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al., 2007 [PubMed 17662026]).
Purification Method: | Affinity purification |
Gene ID: | 255231 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |