MCM8 Rabbit Polyclonal Antibody (CAB12922)
- SKU:
- CAB12922
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Description
Product Name: | MCM8 Rabbit Polyclonal Antibody |
SKU: | CAB12922 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 591-840 of human MCM8 (NP_115874.3). |
Sequence: | FILL DTPN EHHD HLLS EHVI AIRA GKQR TISS ATVA RMNS QDSN TSVL EVVS EKPL SERL KVVP GETI DPIP HQLL RKYI GYAR QYVY PRLS TEAA RVLQ DFYL ELRK QSQR LNSS PITT RQLE SLIR LTEA RARL ELRE EATK EDAE DIVE IMKY SMLG TYSD EFGN LDFE RSQH GSGM SNRS TAKR FISA LNNV AERT YNNI FQFH QLRQ IAKE LNIQ VADF ENFI GSLN DQGY LLKK GPKV YQLQ TM |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | POF10; C20orf154; dJ967N21.5; MCM8 |
Positive Sample: | LO2,HeLa,A-431 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 94kDa |
Observed MW: | 110kDa |
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the mini-chromosome maintenance proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the mini-chromosome maintenance proteins. The encoded protein may interact with other mini-chromosome maintenance proteins and play a role in DNA replication. This gene may be associated with length of reproductive lifespan and menopause. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Purification Method: | Affinity purification |
Gene ID: | 84515 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |