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MCM7 PAT1G8AT Monoclonal Antibody [PAT1G8AT] (CPAB0685)

SKU:
CPAB0685
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT1G8AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

MCM7 PAT1G8AT Monoclonal Antibody [PAT1G8AT] (CPAB0685)

The MCM7 Polyclonal Antibody (CPAB0685) is specifically designed for research involving MCM7, a protein essential for DNA replication and cell proliferation. The antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the MCM7 protein, this antibody allows for effective detection and analysis in a variety of cell types, making it an ideal tool for studies in molecular biology and cancer research.MCM7, part of the minichromosome maintenance (MCM) protein complex, plays a crucial role in ensuring the accurate replication of DNA during cell division. Dysregulation of MCM7 expression has been linked to various cancers and other proliferative disorders, highlighting its importance as a potential therapeutic target.

Understanding the function of MCM7 is fundamental for advancing our knowledge of cell cycle regulation and potentially identifying new strategies for cancer treatment.Overall, the MCM7 Polyclonal Antibody (CPAB0685) provides a valuable tool for researchers interested in studying DNA replication, cell proliferation, and cancer biology. Its high specificity and sensitivity make it a reliable choice for investigations aimed at elucidating the role of MCM7 in normal and disease states.

Product Name:MCM7 PAT1G8AT Antibody
Product Sku:CPAB0685
Size:5μg
Host Species:Mouse
Immunogen:Anti-human MCM7 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human MCM7 protein 1-414 amino acids purified from Ecoli.
Clone:PAT1G8AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:MCM7 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:MCM7 is a highly conserved mini-chromosome maintenance protein (MCM) vital for eukaryotic genome replication initiation. The MCM proteins form a hexameric protein complex which is a key component of the pre-replication complex (pre_RC) which takes part in replication forks formation and in DNA replication related proteins recruitment. The MCM complex is comprised of MCM2, 4, 6 and 7 proteins and possesses DNA helicase activity, such as DNA unwinding.
Synonyms:Minichromosome Maintenance Complex Component 7, MCM7 Minichromosome Maintenance Deficient 7 (S. Cerevisiae), Minichromosome Maintenance Deficient (S. Cerevisiae) 7, DNA Replication Licensing Factor MCM7, Homolog of S. Cerevisiae Cdc47, CDC47 Homolog, P1CDC47, PNAS146, P85MCM, MCM2, CDC47, P1.1-MCM3, EC 3.6.4.12.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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