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MCM7 Monoclonal Antibody [PAT118H7AT] (CPAB0678)

SKU:
CPAB0678
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT118H7AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

MCM7 Monoclonal Antibody [PAT118H7AT] (CPAB0678)

The MCM7 Polyclonal Antibody (CPAB0678) is a valuable tool for research involving MCM7, a protein essential for DNA replication and cell cycle progression. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the MCM7 protein, this antibody allows for the detection and analysis of MCM7 expression in various cell types, making it an ideal tool for studies in molecular biology and cancer research.MCM7 is a crucial component of the MCM complex, which plays a vital role in DNA replication and the maintenance of genomic stability.

Dysregulation of MCM7 has been linked to cancer development and progression, highlighting its importance as a potential therapeutic target. By investigating the function of MCM7, researchers can gain insights into the mechanisms underlying cancer growth and potentially identify novel treatment strategies.Overall, the MCM7 Polyclonal Antibody offers a reliable means of studying MCM7 expression and function in a variety of research settings, providing valuable insights into the role of this protein in both normal and disease states.

Product Name:MCM7 Antibody
Product Sku:CPAB0678
Size:5μg
Host Species:Mouse
Immunogen:Anti-human MCM7 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human MCM7 protein 1-414 amino acids purified from Ecoli.
Clone:PAT118H7AT.
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:MCM7 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG1
Background:MCM7 is a highly conserved mini-chromosome maintenance protein (MCM) vital for eukaryotic genome replication initiation. The MCM proteins form a hexameric protein complex which is a key component of the pre-replication complex (pre_RC) which takes part in replication forks formation and in DNA replication related proteins recruitment. The MCM complex is comprised of MCM2, 4, 6 and 7 proteins and possesses DNA helicase activity, such as DNA unwinding.
Synonyms:Minichromosome Maintenance Complex Component 7, MCM7 Minichromosome Maintenance Deficient 7 (S. Cerevisiae), Minichromosome Maintenance Deficient (S. Cerevisiae) 7, DNA Replication Licensing Factor MCM7, Homolog of S. Cerevisiae Cdc47, CDC47 Homolog, P1CDC47, PNAS146, P85MCM, MCM2, CDC47, P1.1-MCM3, EC 3.6.4.12.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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