MCL1 Polyclonal Antibody (CAB24435)
- SKU:
- CAB24435
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
| Product Name: | MCL1 Polyclonal Antibody |
| SKU: | CAB24435 |
| Size: | 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human MCL1 (NP_068779.1). |
| Sequence: | APTR RAAP LEEM EAPA ADAI MSPE EELD GYEP EPLG KRPA VLPL LELV GESG NNTS TDGS LPST PPPA EEEE DELY RQSL EIIS RYLR EQAT GAKD TKPM G |
| Tested Applications: | WB |
| Recommended Dilution: | WB,1:500 - 1:1000 |
| Synonyms: | TM; EAT; MCL1L; MCL1S; Mcl-1; BCL2L3; MCL1-ES; bcl2-L-3; mcl1/EAT; MCL1 |
| Positive Sample: | Ramos,293T |
| Conjugate: | Unconjugated |
| Cellular Localization: | Cytoplasm, Membrane, Mitochondrion, Nucleus, Single-pass membrane protein, nucleoplasm. |
| Calculated MW: | 37kDa |
| Observed MW: | 40kDa |
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
| Purification Method: | Affinity purification |
| Gene ID: | 4170 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |
 | Western blot analysis of various lysates, using MCL1 Rabbit pAb (CAB24435) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s. |
Related Products
MCL1 Rabbit Polyclonal Antibody (CAB0434)
€139 - €419
