MCL1 Rabbit Polyclonal Antibody (CAB0434)
- SKU:
- CAB0434
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | MCL1 Rabbit Polyclonal Antibody |
SKU: | CAB0434 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-327 of human MCL1 (NP_068779.1). |
Sequence: | MFGL KRNA VIGL NLYC GGAG LGAG SGGA TRPG GRLL ATEK EASA RREI GGGE AGAV IGGS AGAS PPST LTPD SRRV ARPP PIGA EVPD VTAT PARL LFFA PTRR AAPL EEME APAA DAIM SPEE ELDG YEPE PLGK RPAV LPLL ELVG ESGN NTST DGSL PSTP PPAE EEED ELYR QSLE IISR YLRE QATG AKDT KPMG RSGA TSRK ALET LRRV GDGV QRNH ETAF QGML RKLD IKNE DDVK SLSR VMIH VFSD GVTN WGRI VTLI SFGA FVAK HLKT INQE SCIE PLAE SITD VLVR TKRD WLVK QRGW DGFV EFFH VEDL EGG |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | TM; EAT; MCL1L; MCL1S; Mcl-1; BCL2L3; MCL1-ES; bcl2-L-3; mcl1/EAT; MCL1 |
Positive Sample: | Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Membrane, Mitochondrion, Nucleus, Single-pass membrane protein, nucleoplasm. |
Calculated MW: | 37kDa |
Observed MW: | 35kDa |
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
Purification Method: | Affinity purification |
Gene ID: | 4170 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |