MCL1 Rabbit Polyclonal Antibody (CAB0250)
- SKU:
- CAB0250
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
Product Name: | MCL1 Rabbit Polyclonal Antibody |
SKU: | CAB0250 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human MCL1 (NP_068779.1). |
Sequence: | SGNN TSTD GSLP STPP PAEE EEDE LYRQ SLEI ISRY LREQ ATGA KDTK PMGR SGAT SRKA LETL RRVG DGVQ RNHE TAFQ GMLR KLDI KNED DVKS LSRV M |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | TM; EAT; MCL1L; MCL1S; Mcl-1; BCL2L3; MCL1-ES; bcl2-L-3; mcl1/EAT; MCL1 |
Positive Sample: | BT-474,Raji,Mouse lung,Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Membrane, Mitochondrion, Nucleus, Single-pass membrane protein, nucleoplasm. |
Calculated MW: | 37kDa |
Observed MW: | 37kDa |
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
Purification Method: | Affinity purification |
Gene ID: | 4170 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |