UniProt Protein Function: | MCIDAS: Transcription regulator required for multiciliate cell differentiation. Acts by promoting transcription of genes required for multiciliate cell formation. Probably acts in a multiprotein complex. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Belongs to the geminin family. Homodimer. Interacts with GMNN; targets GMNN to the nucleus, prevents GMNN interaction with CDT1 and competes with IDAS homodimerizationChromosomal Location of Human Ortholog: 5q11.2Cellular Component: nucleolus; nucleusMolecular Function: identical protein binding; protein bindingBiological Process: cilium biogenesis; positive regulation of transcription from RNA polymerase II promoter; regulation of mitotic cell cycle |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | D6RGH6 |
NCBI GenInfo Identifier: | 342164929 |
NCBI Gene ID: | 345643 |
NCBI Accession: | D6RGH6.1 |
UniProt Secondary Accession: | D6RGH6,C9JGY3, D6R920, F8KGQ8 |
UniProt Related Accession: | D6RGH6 |
Molecular Weight: | 41,720 Da |
NCBI Full Name: | Multicilin |
NCBI Synonym Full Names: | multiciliate differentiation and DNA synthesis associated cell cycle protein |
NCBI Official Symbol: | MCIDASÂ Â |
NCBI Official Synonym Symbols: | MCI; IDAS; MCINÂ Â |
NCBI Protein Information: | multicilin |
UniProt Protein Name: | Multicilin |
UniProt Synonym Protein Names: | Multiciliate differentiation and DNA synthesis-associated cell cycle protein; Protein Idas |
Protein Family: | Multicilin |
UniProt Gene Name: | MCIDASÂ Â |
UniProt Entry Name: | MCIN_HUMAN |