MCHR2 Antibody (PACO55630)
- SKU:
- PACO55630
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
MCHR2 Antibody (PACO55630)
The MCHR2 Monoclonal Antibody (PACO55630) is a valuable tool for biomedical research focused on the Melanin-concentrating hormone receptor 2 (MCHR2) protein. This antibody, derived from mouse hybridoma cells, exhibits high specificity and sensitivity for detecting MCHR2 in various biological samples, particularly in studies involving neuroscience and metabolic disorders.MCHR2 is a G-protein coupled receptor involved in the regulation of feeding behavior, energy homeostasis, and stress response. Dysregulation of MCHR2 signaling has been implicated in conditions such as obesity, depression, and diabetes, making it a promising therapeutic target for drug development.
The availability of the PACO55630 antibody provides researchers with a reliable tool for investigating the expression and function of MCHR2 in different cell types and tissues.By utilizing the MCHR2 Monoclonal Antibody (PACO55630) in techniques such as immunofluorescence and immunohistochemistry, scientists can gain valuable insights into the role of MCHR2 in various physiological processes and disease states. This antibody's compatibility with multiple experimental approaches makes it an essential component in studies aimed at elucidating the molecular mechanisms underlying MCHR2 function and its potential implications for human health.
| Antibody Name: | MCHR2 Antibody (PACO55630) |
| Antibody SKU: | PACO55630 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Melanin-concentrating hormone receptor 2 protein (1-39AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO55630 diluted at 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | Immunofluorescence staining of Hela cells with PACO55630 at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis. |
| Synonyms: | Melanin-concentrating hormone receptor 2 (MCH receptor 2) (MCH-R2) (MCHR-2) (G-protein coupled receptor 145) (GPRv17) (MCH-2R) (MCH2) (MCH2R), MCHR2, GPR145 SLT |
| UniProt Protein Function: | MCHR2: Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR Chromosomal Location of Human Ortholog: 6q16 Cellular Component: plasma membrane; integral to membrane Molecular Function:G-protein coupled receptor activity Biological Process: G-protein coupled receptor protein signaling pathway |
| UniProt Code: | Q969V1 |
| NCBI GenInfo Identifier: | 119220588 |
| NCBI Gene ID: | 84539 |
| NCBI Accession: | NP_115892 |
| UniProt Related Accession: | Q969V1 |
| Molecular Weight: | 39kDa |
| NCBI Full Name: | melanin-concentrating hormone receptor 2 |
| NCBI Synonym Full Names: | melanin concentrating hormone receptor 2 |
| NCBI Official Symbol: | MCHR2Â Â |
| NCBI Official Synonym Symbols: | SLT; MCH2; MCH2R; GPR145; GPRv17; MCH-2R; MCH-R2; MCHR-2Â Â |
| NCBI Protein Information: | melanin-concentrating hormone receptor 2 |
| UniProt Protein Name: | Melanin-concentrating hormone receptor 2 |
| UniProt Synonym Protein Names: | G-protein coupled receptor 145; GPRv17; MCH-2R |
| Protein Family: | Melanin-concentrating hormone receptor |
| UniProt Gene Name: | MCHR2Â Â |
| UniProt Entry Name: | MCHR2_HUMAN |
| Antibodies | ELISA Kits |
| MCHR2 Antibody (PACO05522) | Human Melanin-concentrating hormone receptor 2 / MCHR2 ELISA Kit |
| Human Melanin-concentrating hormone receptor 2 (MCHR2) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
MCHR2 Antibody (PACO05522)
Human Melanin-concentrating hormone receptor 2 (MCHR2) ELISA Kit (HUEB1175)
Human Melanin-concentrating hormone receptor 2 / MCHR2 ELISA Kit
