The MCHR1 Polyclonal Antibody (CAB18111) is a valuable tool for researchers studying the Melanin-concentrating hormone receptor 1 (MCHR1) protein. This antibody, raised in rabbits, is highly specific for the human MCHR1 protein and is validated for use in Western blot applications. By binding to the MCHR1 protein, this antibody allows for the detection and analysis of MCHR1 in various cell types, making it ideal for research in neuroscience, obesity, and metabolic disorders.MCHR1 is a G-protein coupled receptor that plays a crucial role in the regulation of feeding behavior, energy homeostasis, and stress response.
Dysregulation of MCHR1 has been implicated in obesity, depression, and other metabolic disorders, making it a promising target for therapeutic interventions. Understanding the function and regulation of MCHR1 is essential for the development of novel treatments for these conditions.Overall, the MCHR1 Polyclonal Antibody is a valuable tool for researchers investigating the role of MCHR1 in various physiological and pathological processes. Its high specificity and reactivity make it a reliable choice for studies aiming to elucidate the function of MCHR1 and its potential as a therapeutic target.
Product Name:
MCHR1 Rabbit Polyclonal Antibody
SKU:
CAB18111
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human MCHR1 (NP_005288.3).
The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin.
Purification Method:
Affinity purification
Gene ID:
2847
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MCHR1 Rabbit pAb (CAB18111) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
