The MCF2 Polyclonal Antibody (CAB12839) is a valuable tool for researchers studying MCF2, a protein involved in cell signaling and cytoskeletal dynamics. This antibody is raised in rabbits and exhibits high reactivity with human samples, making it suitable for use in Western blot applications. By binding specifically to the MCF2 protein, this antibody enables researchers to detect and analyze MCF2 expression in various cell types, providing insights into its role in cellular processes.MCF2, also known as guanine nucleotide exchange factor, plays a crucial role in the regulation of cell growth, proliferation, and migration.
Its involvement in signaling pathways related to cancer, neurodegenerative diseases, and other conditions makes it a promising target for research and potential therapeutic interventions. By investigating the function of MCF2, researchers can gain a better understanding of its impact on disease development and progression, leading to the identification of novel treatment strategies.
Product Name:
MCF2 Rabbit Polyclonal Antibody
SKU:
CAB12839
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 872-1001 of human MCF2 (NP_001165347.1).
The oncogenic protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that exerts control over some members of the Rho family of small GTPases. Several transcript variants encoding different isoforms have been found for this gene. These isoforms exhibit different expression patterns and varying levels of GEF activity.
Purification Method:
Affinity purification
Gene ID:
4168
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HT-29 cells, using MCF2 Rabbit pAb (CAB12839) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
