The MCAM Polyclonal Antibody (CAB13927) is a crucial tool for researchers studying MCAM, a cell surface protein involved in various biological processes, including cell adhesion and migration. This antibody, generated in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the MCAM protein, researchers can accurately detect and analyze its expression in different cell types, making it an ideal choice for studies in cell biology, cancer research, and immunology.MCAM, also known as Melanoma Cell Adhesion Molecule, plays a key role in cell adhesion and migration processes, making it a potential target for therapeutic interventions in cancer metastasis.
Its expression has been linked to tumorigenesis, angiogenesis, and metastasis, highlighting its significance in cancer progression. Understanding the function of MCAM can provide valuable insights into tumor development and potentially lead to the development of targeted therapies for cancer treatment.Overall, the MCAM Polyclonal Antibody (CAB13927) is a valuable tool for researchers interested in studying the role of MCAM in various biological processes, particularly in cancer biology. Its specificity and sensitivity make it an excellent choice for detecting MCAM expression and conducting further research into the molecular mechanisms underlying its function.
Product Name:
CD146/MCAM Rabbit Polyclonal Antibody
SKU:
CAB13927
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 26-350 of human CD146/MCAM (NP_006491.2).
Involved in glomerular filtration and vascular wound healing. Acts upstream of or within angiogenesis. Located in external side of plasma membrane. Biomarker of chronic obstructive pulmonary disease and uveal melanoma.
Purification Method:
Affinity purification
Gene ID:
4162
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using CD146/MCAM Rabbit pAb (CAB13927) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
