The MC3R Polyclonal Antibody (CAB11609) is a versatile tool for researchers studying the melanocortin 3 receptor (MC3R) protein. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the MC3R protein, this antibody allows for the accurate detection and analysis of MC3R expression in various cell types.The MC3R protein is a G protein-coupled receptor involved in the regulation of energy homeostasis and metabolism. It plays a crucial role in mediating the effects of melanocortin peptides, which are key regulators of appetite and energy expenditure.
Dysfunction of the MC3R receptor has been linked to obesity, metabolic disorders, and other diseases related to energy balance.By using the MC3R Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of the MC3R receptor in physiological and pathological conditions. This antibody is an essential tool for studies in obesity, diabetes, and other metabolic disorders, as well as for the development of potential therapies targeting the MC3R pathway.
Product Name:
MC3R Rabbit Polyclonal Antibody
SKU:
CAB11609
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human MC3R (NP_063941.3).
This gene encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans.
Purification Method:
Affinity purification
Gene ID:
4159
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MC3R Rabbit pAb (CAB11609) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
