The MBTPS1 Polyclonal Antibody (CAB13379) is a valuable tool for researchers studying MBTPS1, a membrane-bound transcription factor implicated in various biological processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the MBTPS1 protein, this antibody enables accurate detection and analysis in a wide range of cell types, making it ideal for studies in cell biology, signaling pathways, and protein processing.MBTPS1 is known to play a key role in the regulation of protein folding and processing, making it a crucial factor in cellular homeostasis.
Dysregulation of MBTPS1 has been linked to various diseases, including neurological disorders and cancer. By understanding the function and regulation of MBTPS1, researchers can gain insights into the mechanisms underlying these diseases, paving the way for the development of targeted therapies.Overall, the MBTPS1 Polyclonal Antibody is a valuable tool for researchers seeking to unravel the complex biological functions of MBTPS1 and its role in disease pathogenesis. Its high specificity and sensitivity make it a reliable choice for immunological studies and drug development research.
Product Name:
MBTPS1 Rabbit Polyclonal Antibody
SKU:
CAB13379
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 803-1052 of human MBTPS1 (NP_003782.1).
Endoplasmic reticulum membrane, Golgi apparatus membrane, Single-pass type I membrane protein.
Calculated MW:
118kDa
This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction.
Purification Method:
Affinity purification
Gene ID:
8720
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human colon cancer using MBTPS1 Rabbit pAb (CAB13379) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
