The MBNL2 Polyclonal Antibody (CAB12838) is a valuable tool for researchers studying MBNL2, a protein involved in RNA splicing and regulation. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the MBNL2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an excellent choice for studies in molecular biology and genetic research.MBNL2 is known for its role in alternative splicing regulation and has been implicated in various diseases, including myotonic dystrophy and cancer.
By studying the function of MBNL2, researchers can gain valuable insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets. The MBNL2 Polyclonal Antibody is a powerful tool for investigating the role of this protein in various biological processes, offering valuable opportunities for advancing scientific knowledge and biomedical research.
Product Name:
MBNL2 Rabbit Polyclonal Antibody
SKU:
CAB12838
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 160-260 of human MBNL2 (NP_659002.1).
This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined.
Purification Method:
Affinity purification
Gene ID:
10150
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MBNL2 Rabbit pAb (CAB12838) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
