The MBL2 Polyclonal Antibody (CAB5825) is a valuable tool for researchers studying the Mannose-Binding Lectin 2 (MBL2) protein. MBL2 is a key component of the innate immune system, playing a critical role in pathogen recognition and clearance. This antibody, raised in rabbits, is highly specific to human samples and is validated for use in Western blot applications.By binding to the MBL2 protein, this antibody allows for the detection and analysis of MBL2 in various cell types, providing valuable insights into its function in the immune response.
Research involving MBL2 is essential for understanding the mechanisms underlying infectious diseases, autoimmune disorders, and inflammatory conditions.With its high reactivity and specificity, the MBL2 Polyclonal Antibody (CAB5825) is a reliable tool for investigating the role of MBL2 in disease pathology and developing targeted therapies. Researchers in the fields of immunology, infectious diseases, and inflammation will find this antibody to be an essential asset in their studies.
Product Name:
MBL2 Rabbit Polyclonal Antibody
SKU:
CAB5825
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-248 of human MBL2 (NP_000233.1).
This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes and binds to mannose and N-acetylglucosamine on many microorganisms, including bacteria, yeast, and viruses including influenza virus, HIV and SARS-CoV. This binding activates the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.
Purification Method:
Affinity purification
Gene ID:
4153
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse serum, using MBL2 Rabbit pAb (CAB5825) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
