The MAVS Polyclonal Antibody (CAB5764) is a research tool specifically designed for studying mitochondrial antiviral signaling protein (MAVS), a key player in the innate immune response against viral infections. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the MAVS protein, researchers can effectively detect and analyze its expression in various cell types, making it an essential tool for studies in virology and immunology.
MAVS is essential for triggering antiviral immune responses by activating downstream signaling pathways that lead to the production of interferons and pro-inflammatory cytokines. Understanding the mechanisms by which MAVS functions is crucial for developing therapeutics against viral infections and other related diseases. By utilizing the MAVS Polyclonal Antibody, researchers can unravel the intricate roles of MAVS in host defense, paving the way for innovative approaches in antiviral therapy and vaccine development.
Product Name:
MAVS Rabbit Polyclonal Antibody
SKU:
CAB5764
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAVS (NP_065797.2).
This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral innate immunity.
Purification Method:
Affinity purification
Gene ID:
57506
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using MAVS Rabbit pAb (CAB5764) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
