The MATR3 Polyclonal Antibody (CAB5905) is a vital tool for researchers studying MATR3, a nuclear matrix protein involved in gene regulation, mRNA processing, and RNA stability. This antibody, produced in rabbits, exhibits high specificity and sensitivity in detecting MATR3 in human samples, making it ideal for various research applications such as Western blot and immunohistochemistry.MATR3 is a multifunctional protein that plays a key role in maintaining cellular homeostasis and gene expression. Dysregulation of MATR3 has been implicated in neurodegenerative diseases, muscular dystrophies, and cancer, highlighting its importance in various pathophysiological processes.
By using the MATR3 Polyclonal Antibody, researchers can gain insights into the molecular mechanisms governed by MATR3 and potentially identify novel therapeutic targets for treating MATR3-related disorders.Overall, the MATR3 Polyclonal Antibody is a valuable tool for researchers in the fields of molecular biology, genetics, and neuroscience who are investigating the roles of MATR3 in health and disease. Its reliability and specificity make it a crucial asset for conducting experiments and advancing our understanding of MATR3 biology.
Product Name:
Matrin 3 Rabbit Polyclonal Antibody
SKU:
CAB5905
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 747-847 of human Matrin 3 (NP_001181884.1).
Sequence:
SSEN ADDP NKDT SENA DGQS DENK DDYT IPDE YRIG PYQP NVPV GIDY VIPK TGFY CKLC SLFY TNEE VAKN THCS SLPH YQKL KKFL NKLA EERR QKKE T
This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Mutations of this gene are associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts composed of the upstream small nucleolar RNA host gene 4 (non-protein coding) and matrin 3 gene sequence, have been identified. Pseudogenes of this gene are located on chromosomes 1 and X.
Purification Method:
Affinity purification
Gene ID:
9782
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Matrin 3 Rabbit pAb (CAB5905) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
