The Matrilin-4 Polyclonal Antibody (CAB2761) is a versatile tool for research involving Matrilin-4, a protein belonging to the extracellular matrix family with important roles in cartilage development and maintenance. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications including Western blot and immunohistochemistry.Matrilin-4 is known for its involvement in the formation and maintenance of cartilage tissues, making it a key target for studies in musculoskeletal biology and diseases such as osteoarthritis.
Its interaction with other extracellular matrix components and signaling molecules highlights its importance in tissue homeostasis and repair processes.By using the Matrilin-4 Polyclonal Antibody, researchers can gain valuable insights into the function and expression of Matrilin-4 in different biological contexts, paving the way for a better understanding of cartilage development, maintenance, and pathologies. This antibody is a valuable tool for advancing research in the fields of orthopedics, rheumatology, and tissue engineering.
Product Name:
MATN4 Rabbit Polyclonal Antibody
SKU:
CAB2761
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 221-540 of human MATN4 (NP_085080.1).
This gene encodes a member of von Willebrand factor A domain-containing protein family. The proteins of this family are thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This family member is thought to be play a role in reorganizing and regenerating the corneal matrix in granular and lattice type I dystrophies. It may also be involved in wound healing in the dentin-pulp complex. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
8785
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MATN4 Rabbit pAb (CAB2761) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
