The MATN1 Polyclonal Antibody (PAC018189) is specifically designed for research involving MATN1, a protein that plays a key role in extracellular matrix formation and maintenance. This antibody, raised in rabbits, has shown high reactivity with human samples and is validated for use in various applications such as Western blot and immunohistochemistry.MATN1, also known as matrilin-1, is involved in processes such as cartilage development, cell adhesion, and regulation of cell proliferation. Its importance in tissue integrity and function makes it a promising target for research in musculoskeletal disorders, cartilage regeneration, and cancer metastasis studies.
By utilizing the MATN1 Polyclonal Antibody, researchers can efficiently detect and analyze the expression of MATN1 in different cell types and tissues, providing valuable insights into its function and potential therapeutic implications. This antibody is a valuable tool for investigators in the fields of biology, biochemistry, and medicine looking to advance their understanding of MATN1 biology and its implications in various disease states.
Antibody Name:
MATN1 Antibody (PACO18189)
Antibody SKU:
PACO18189
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human MATN1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO18189(MATN1 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO18189(MATN1 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins are thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. Mutations of this gene have been associated with variety of inherited chondrodysplasias.
Synonyms:
matrilin 1, cartilage matrix protein
UniProt Protein Function:
MATN1: Cartilage matrix protein is a major component of the extracellular matrix of non-articular cartilage. It binds to collagen.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 1p35Cellular Component: extracellular regionMolecular Function: protein bindingBiological Process: extracellular matrix organization and biogenesis; protein complex assembly
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of von Willebrand factor A domain containing protein family. This family of proteins are thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. Mutations of this gene have been associated with variety of inherited chondrodysplasias. [provided by RefSeq, Jul 2008]
