MATK Rabbit Polyclonal Antibody (CAB6651)
- SKU:
- CAB6651
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | MATK Rabbit Polyclonal Antibody |
SKU: | CAB6651 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 352-466 of human MATK (NP_647611.1). |
Sequence: | PEAL KHGK FTSK SDVW SFGV LLWE VFSY GRAP YPKM SLKE VSEA VEKG YRME PPEG CPGP VHVL MSSC WEAE PARR PPFR KLAE KLAR ELRS AGAP ASVS GQDA DGST SPRS QEP |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | CHK; CTK; HYL; Lsk; HYLTK; HHYLTK; MATK |
Positive Sample: | THP-1 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Membrane. |
Calculated MW: | 56kDa |
Observed MW: | 56kDa |
The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.
Purification Method: | Affinity purification |
Gene ID: | 4145 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |