The MAT2A Polyclonal Antibody (CAB8436) is a valuable tool for researchers studying MAT2A, an essential enzyme involved in the methionine adenosyltransferase pathway. This antibody, produced in rabbits, exhibits strong reactivity with human samples and has been validated for use in applications such as Western blotting.MAT2A plays a critical role in methylation processes, which are involved in various cellular functions such as gene expression regulation and protein synthesis. Dysregulation of MAT2A has been linked to various diseases including cancer, liver disorders, and neurological conditions, making it a promising therapeutic target.
By detecting and studying MAT2A expression levels and function in different cell types, researchers can gain insight into its role in disease progression and potentially identify new treatment strategies. The MAT2A Polyclonal Antibody is a reliable tool for these studies, providing accurate and specific detection of MAT2A protein for advanced research in biochemistry, molecular biology, and drug development.
Product Name:
MAT2A Rabbit Polyclonal Antibody
SKU:
CAB8436
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-395 of human MAT2A (NP_005902.1).
The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes.
Purification Method:
Affinity purification
Gene ID:
4144
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MAT2A antibody (CAB8436) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.