Based on the information provided in the URL, the Mast1 Antibody (PAC047270) is a polyclonal antibody designed for research involving Mast1, a protein encoded by the Mast1 gene. Mast1 is known to play a role in regulating cellular processes such as cell division and differentiation, making it a valuable target for studies in cell biology and cancer research.The antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blotting. By binding specifically to the Mast1 protein, this antibody enables the detection and analysis of Mast1 expression in different cell types, making it an ideal tool for investigating the function of Mast1 in cellular pathways and disease processes.
Mast1 is implicated in various cellular functions, including cell cycle regulation and signaling pathways related to cancer development. Research on Mast1 may provide insights into the mechanisms underlying tumorigenesis and potentially lead to the identification of novel therapeutic targets for cancer treatment. By studying the activity of Mast1, researchers can gain a better understanding of its role in cell biology and its potential implications for human health.
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO47270 at dilution of 1:100.
Immunofluorescent analysis of Hela cells using PACO47270 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunohistochemistry of paraffin-embedded human brain tissue using PACO47270 at dilution of 1:100.
Background:
Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins (By similarity).
MAST1: Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.Protein type: Protein kinase, AGC; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Kinase, protein; AGC group; MAST familyChromosomal Location of Human Ortholog: 19p13.2Cellular Component: intracellularMolecular Function: ATP binding; magnesium ion binding; protein binding; protein serine/threonine kinase activityBiological Process: cytoskeleton organization and biogenesis; peptidyl-serine phosphorylation; protein amino acid phosphorylation
