MASP2 Rabbit Polyclonal Antibody (CAB16030)
- SKU:
- CAB16030
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | MASP2 Rabbit Polyclonal Antibody |
SKU: | CAB16030 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 445-686 of human MASP2 (NP_006601.2). |
Sequence: | IYGG QKAK PGDF PWQV LILG GTTA AGAL LYDN WVLT AAHA VYEQ KHDA SALD IRMG TLKR LSPH YTQA WSEA VFIH EGYT HDAG FDND IALI KLNN KVVI NSNI TPIC LPRK EAES FMRT DDIG TASG WGLT QRGF LARN LMYV DIPI VDHQ KCTA AYEK PPYP RGSV TANM LCAG LESG GKDS CRGD SGGA LVFL DSET ERWF VGGI VSWG SMNC GEAG QYGV YTKV INYI PWIE NIIS DF |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | sMAP; MAP-2; MAP19; MASP-2; MASP1P1; MASP2 |
Positive Sample: | HepG2,U-87MG,Mouse liver,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | external side of plasma membrane, extracellular exosome, extracellular region, extracellular space |
Calculated MW: | 76kDa |
Observed MW: | 76kDa |
This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Purification Method: | Affinity purification |
Gene ID: | 10747 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |