The Mark2 Polyclonal Antibody (CAB16706) is a valuable tool for researchers studying the Mark2 protein, a key regulator of cell signaling pathways. This high-quality antibody, produced in rabbits, offers strong reactivity with human samples and has been validated for use in Western blot applications.Mark2, also known as MARK2 or MAP/microtubule affinity-regulating kinase 2, is involved in various cellular processes such as cell polarity, cell migration, and cytoskeletal organization. Dysregulation of Mark2 has been associated with diseases such as cancer, neurodegenerative disorders, and metabolic diseases, highlighting its importance in biological processes.
By using the Mark2 Polyclonal Antibody, researchers can effectively detect and analyze the presence of Mark2 protein in different cell types, providing insights into its role in cellular functions and disease development. This antibody is a valuable tool for studies in cell biology, cancer research, and drug discovery, ultimately contributing to the advancement of scientific knowledge and potential therapeutic interventions.
Product Name:
MARK2 Rabbit Polyclonal Antibody
SKU:
CAB16706
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 350-455 of human MARK2 (Q7KZI7).
This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
2011
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MARK2 Rabbit pAb (CAB16706) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
