The Marcksl1 Polyclonal Antibody (CAB10006) is specifically designed for research involving Marcksl1, a protein associated with cell movement and function. This antibody, produced in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the Marcksl1 protein, this antibody enables detection and analysis in various cell types, making it an essential tool for studies in cell biology and cancer research.Marcksl1, also known as Myristoylated alanine-rich C-kinase substrate-like 1, is a key regulator of cell motility and has been implicated in cancer progression and metastasis.
Its role in cellular processes makes it a valuable target for research into cancer biology and therapeutic development. Understanding the function of Marcksl1 is essential for identifying potential therapeutic targets and developing strategies to inhibit cancer metastasis.Overall, the Marcksl1 Polyclonal Antibody is a valuable tool for researchers studying cell movement, cancer biology, and therapeutic development. Its high reactivity and specificity make it an ideal choice for Western blot applications and enable precise detection and analysis of the Marcksl1 protein in various cell types.
Product Name:
MARCKSL1 Polyclonal Antibody
SKU:
CAB24471
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 95-195 of human MARCKSL1 (NP_075385.1).
MARCKSL1; F52; MACMARCKS; MLP; MLP1; MRP; MARCKS like 1
Positive Sample:
293T,SH-SY5Y,Mouse thymus,Rat testis
Conjugate:
Unconjugated
Cellular Localization:
Cell membrane, Cytoplasm, Lipid-anchor, Membrane.
Calculated MW:
19kDa
Observed MW:
40kDa
This gene encodes a member of the myristoylated alanine-rich C-kinase substrate (MARCKS) family. Members of this family play a role in cytoskeletal regulation, protein kinase C signaling and calmodulin signaling. The encoded protein affects the formation of adherens junction. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on the long arm of chromosomes 6 and 10.
Purification Method:
Affinity purification
Gene ID:
65108
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using MARCKSL1 Rabbit pAb (CAB24471) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
