The MARCKSL1 Polyclonal Antibody (CAB7132) is a valuable tool for researchers studying MARCKSL1, a protein involved in cell signaling and regulation of actin cytoskeleton dynamics. This antibody, produced in rabbits, has been validated for use in various applications, including Western blot and immunohistochemistry.MARCKSL1, also known as MARCKS-related protein, plays a critical role in cellular processes such as cell motility, adhesion, and proliferation. Dysregulation of MARCKSL1 expression has been linked to cancer progression and metastasis, making it a promising target for drug development and therapeutic intervention.
By using the MARCKSL1 Polyclonal Antibody, researchers can study the expression and function of MARCKSL1 in different cell types and tissues, providing valuable insights into its potential role in disease pathology. This antibody is a valuable tool for investigations into cancer biology, particularly in understanding the mechanisms by which MARCKSL1 influences tumor growth and spread.
Product Name:
MARCKSL1 Rabbit Polyclonal Antibody
SKU:
CAB7132
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human MARCKSL1 (NP_075385.1).
This gene encodes a member of the myristoylated alanine-rich C-kinase substrate (MARCKS) family. Members of this family play a role in cytoskeletal regulation, protein kinase C signaling and calmodulin signaling. The encoded protein affects the formation of adherens junction. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on the long arm of chromosomes 6 and 10.
Purification Method:
Affinity purification
Gene ID:
65108
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MARCKSL1 antibody (CAB7132) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
