MARCKS Rabbit Polyclonal Antibody (CAB0936)
- SKU:
- CAB0936
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MARCKS Rabbit Polyclonal Antibody |
SKU: | CAB0936 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MARCKS (NP_002347.5). |
Sequence: | MGAQ FSKT AAKG EAAA ERPG EAAV ASSP SKAN GQEN GHVK VNGD ASPA AAES GAKE ELQA NGSA PAAD KEEP AAAG SGAA SPSA AEKG EPAA AAAP EAGA |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | MACS; 80K-L; PKCSL; PRKCSL; MARCKS |
Positive Sample: | Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Lipid-anchor, Membrane, cytoskeleton. |
Calculated MW: | 32kDa |
Observed MW: | 80kDa |
The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
Purification Method: | Affinity purification |
Gene ID: | 4082 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |