MARCH9 Rabbit Polyclonal Antibody (CAB10596)
- SKU:
- CAB10596
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | MARCH9 Rabbit Polyclonal Antibody |
SKU: | CAB10596 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 277-346 of human MARCH9 (NP_612405.2). |
Sequence: | GTAG KSGP RNSR TGPT SGAT SRPP AAQR MRTL LPQR CGYT ILHL LGQL RPPD ARSS SHSG REVV MRVT TV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | MARCH9; RNF179; MARCH-IX |
Positive Sample: | 293T |
Conjugate: | Unconjugated |
Cellular Localization: | Golgi apparatus membrane, Lysosome membrane, Multi-pass membrane protein. |
Calculated MW: | 38kDa |
Observed MW: | 36kDa |
MARCH9 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH9 induces internalization of several membrane glycoproteins and directs them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]; Hoer et al., 2007 [PubMed 17174307]).
Purification Method: | Affinity purification |
Gene ID: | 92979 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |