The MAPK3 Polyclonal Antibody (CAB0228) is a crucial tool for researchers studying the MAPK3 protein, a key player in the MAPK signaling pathway responsible for a variety of cellular processes including proliferation, differentiation, and apoptosis. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.MAPK3, also known as ERK1, is involved in various physiological and pathological processes, making it a valuable target for research in areas such as cancer, neurodegenerative diseases, and cardiovascular disorders.
By targeting MAPK3 with this antibody, researchers can accurately detect and analyze the protein in different cell types, providing valuable insights into its function and potential therapeutic applications.Understanding the role of MAPK3 in cellular signaling pathways is essential for advancing our knowledge of disease mechanisms and developing targeted therapies. The MAPK3 Polyclonal Antibody is a reliable tool for investigating the complex functions of this protein and its implications in various biological processes.
Product Name:
[KO Validated] ERK1 Rabbit Polyclonal Antibody
SKU:
CAB0228
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human ERK1 (NP_002737.2).
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
5595
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using [KD Validated] ERK1 Rabbit pAb (CAB0228) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
