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MAPK3 Monoclonal Antibody [PAT1A2AT] (CPAB0102)

SKU:
CPAB0102
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT1A2AT
Applications:
WB
IF
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

MAPK3 Monoclonal Antibody [PAT1A2AT] (CPAB0102)

The MAPK3 Polyclonal Antibody (CPAB0102) is specifically designed for research involving MAPK3, a key signaling molecule in the MAPK pathway essential for cellular processes such as proliferation, differentiation, and apoptosis. Raised in rabbits, this antibody is highly reactive with human samples and is validated for use in Western blot applications. It binds to the MAPK3 protein, allowing for accurate detection and analysis in a variety of cell types, making it an excellent tool for studies in molecular biology and cancer research.MAPK3, also known as Extracellular Signal-regulated Kinase 1 (ERK1), is a vital player in cell signaling pathways that regulate cell growth and survival.

Dysregulation of MAPK3 has been implicated in various diseases, including cancer, cardiovascular disorders, and neurological conditions. By studying the role of MAPK3 in these pathologies, researchers can gain valuable insights into disease mechanisms and potential therapeutic targets for intervention.Overall, the MAPK3 Polyclonal Antibody is a valuable tool for researchers investigating the intricate signaling pathways involving MAPK3 and its implications in various disease states. Its high specificity and sensitivity make it a reliable choice for experiments aimed at understanding the functional significance of MAPK3 in physiological and pathological conditions.

Product Name:MAPK3 Antibody
Product Sku:CPAB0102
Size:5μg
Host Species:Mouse
Immunogen:Anti-human MAPK3 mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human MAPK3 amino acids 1-137 purified from Ecoli.
Clone:PAT1A2AT.
Reactivity:Human
Applications:Western Blot, Immunofluorescence, ELISA
Purification Method:MAPK3 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:Extracellular signal-regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinaseintracellular signalingmolecules which are involved in functions including the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells. Many different stimuli, including growth factors, cytokines, virusinfection, ligands for heterotrimeric G protein-coupled receptors, transforming agents, and carcinogens, activate the ERK pathway. The term, "extracellular signal-regulated kinases", is sometimes used as a synonym for mitogen-activated protein kinase(MAPK), but has more recently been adopted for a specific subset of the mammalianMAPK family. In the MAPK/ERK pathway, Rasactivates c-Raf, followed by MEKand then MAPK1/2 (below). Ras is typically activated by growth hormones through receptor tyrosine kinasesand GRB2/SOS, but may also receive other signals. ERKs are known to activate many transcription factors and some downstream protein kinases. Disruption of th
Synonyms:Mitogen-activated protein kinase 3, EC 2.7.11.24, Extracellular signal-regulated kinase 1, ERK-1, Insulin-stimulated MAP2 kinase, MAP kinase 1, MAPK 1, p44-ERK1, ERT2, p44-MAPK, Microtubule-associated protein 2 kinase, ERK1, PRKM3, P44ERK1, P44MAPK, HS44KDAP, HUMKER1A, MGC20180.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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