The MAPK13 Polyclonal Antibody (CAB16961) is a valuable tool for researchers studying the MAPK13 protein, a member of the mitogen-activated protein kinase (MAPK) family that plays a crucial role in various cellular processes such as cell growth, differentiation, and apoptosis. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.MAPK13, also known as p38delta, is involved in signaling pathways that regulate inflammation, stress response, and cell survival. Dysregulation of MAPK13 has been linked to various diseases, including cancer, cardiovascular disorders, and neurodegenerative conditions.
By using the MAPK13 Polyclonal Antibody, researchers can accurately detect and analyze MAPK13 expression in different cell types, facilitating research in areas such as immunology, oncology, and drug development.Understanding the role of MAPK13 in cellular signaling pathways is essential for identifying potential therapeutic targets and developing new treatments for diseases associated with MAPK13 dysregulation. The MAPK13 Polyclonal Antibody offers a reliable tool for investigating the function of MAPK13 and its implications in health and disease.
Product Name:
MAPK13 Rabbit Polyclonal Antibody
SKU:
CAB16961
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human MAPK13 (O15264).
This gene encodes a member of the mitogen-activated protein (MAP) kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The encoded protein is a p38 MAP kinase and is activated by proinflammatory cytokines and cellular stress. Substrates of the encoded protein include the transcription factor ATF2 and the microtubule dynamics regulator stathmin. Alternatively spliced transcript variants have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
5603
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MAPK13 Rabbit pAb (CAB16961) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
