The MAPK13 Polyclonal Antibody (CAB7496) is a powerful tool for research involving the MAPK13 protein, a member of the mitogen-activated protein kinase (MAPK) family. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding to the MAPK13 protein, this antibody allows for accurate detection and analysis in various cell types, making it a valuable asset for studies in cell signaling, inflammation, and cancer research.MAPK13 is a key regulator of cellular processes such as cell proliferation, differentiation, and apoptosis. Its role in signaling pathways makes it a promising target for research into diseases like cancer, where dysregulation of MAPK13 activity can contribute to tumor growth and progression.
Understanding the function of MAPK13 is essential for developing targeted therapies that can manipulate cell signaling pathways to combat disease.The MAPK13 Polyclonal Antibody offers researchers the ability to study the expression and activity of MAPK13 in different experimental settings, providing valuable insights into the molecular mechanisms underlying various biological processes. With its specificity and reliability, this antibody is an indispensable tool for advancing our understanding of MAPK13 and its implications in disease pathology.
Product Name:
MAPK13 Rabbit Polyclonal Antibody
SKU:
CAB7496
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-365 of human MAPK13 (NP_002745.1).
This gene encodes a member of the mitogen-activated protein (MAP) kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The encoded protein is a p38 MAP kinase and is activated by proinflammatory cytokines and cellular stress. Substrates of the encoded protein include the transcription factor ATF2 and the microtubule dynamics regulator stathmin. Alternatively spliced transcript variants have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
5603
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MAPK13 antibody (CAB7496) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
