The MAPK12 Polyclonal Antibody (CAB13046) is a valuable tool for researchers studying the mitogen-activated protein kinase 12 (MAPK12) protein, which is involved in various cellular processes, including cell proliferation, differentiation, and apoptosis. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.MAPK12, also known as ERK6, is a member of the MAP kinase family and plays a crucial role in signal transduction pathways that are important for cell growth and survival. Dysregulation of MAPK12 has been implicated in various diseases, including cancer, inflammatory disorders, and neurodegenerative conditions.
By using the MAPK12 Polyclonal Antibody, researchers can study the expression and activity of MAPK12 in different cell types and tissues, providing valuable insights into its role in health and disease.Overall, the MAPK12 Polyclonal Antibody is a versatile tool for investigating the function and regulation of the MAPK12 protein, making it a valuable asset for research in areas such as cancer biology, immunology, and drug discovery.
Product Name:
MAPK12 Rabbit Polyclonal Antibody
SKU:
CAB13046
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 248-367 of human MAPK12 (NP_002960.2).
Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes.
Purification Method:
Affinity purification
Gene ID:
6300
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MAPK12 Rabbit pAb (CAB13046) at 1:10000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
