The MAPK11 Polyclonal Antibody (CAB7717) is a valuable tool for researchers studying the MAPK11 protein, which plays a key role in cellular signaling pathways associated with inflammation and immune response. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the MAPK11 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in immunology, inflammation, and cancer research.MAPK11, also known as p38β, is a member of the MAPK signaling pathway that regulates a wide range of cellular processes, including cell proliferation, differentiation, and survival.
Its involvement in inflammatory responses and immune cell activation makes it a promising target for the development of therapeutic interventions in conditions such as autoimmune diseases, inflammatory disorders, and cancer. By studying the function and regulation of MAPK11, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new treatment strategies.
Product Name:
MAPK11 Rabbit Polyclonal Antibody
SKU:
CAB7717
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 264-364 of human MAPK11 (NP_002742.3).
This gene encodes a member of a family of protein kinases that are involved in the integration of biochemical signals for a wide variety of cellular processes, including cell proliferation, differentiation, transcriptional regulation, and development. The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs). Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5600
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using MAPK11 Rabbit pAb (CAB7717) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.
