MAPK1/MAPK3 Rabbit Polyclonal Antibody (CAB17291)
- SKU:
- CAB17291
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MAPK1/MAPK3 Rabbit Polyclonal Antibody |
SKU: | CAB17291 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human MAPK1/MAPK3ERK1/2 (P27361/P28482). |
Sequence: | FLTE YVAT RWYR APEI MLNS KGYT KSID IWSV GCIL AEML SNRP IFPG KHYL DQLN HILG ILGS PSQE DLNC IINM KARN YLQS LPSK TKVA WAKL FPKS D/LN SKGY TKSI DIWS VGCI LAEM LSNR PIFP GKHY LDQL NHIL GILG SPSQ EDLN CIIN LKAR NYLL SLPH KNKV PWNR LFPN ADSK ALDL LDKM LTFN PHK |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | MAPK1/MAPK3 |
Positive Sample: | 293T,NIH/3T3 |
Cellular Localization: | caveola, cytoplasm, cytoskeleton, cytosol, early endosome, endoplasmic reticulum lumen, extracellular region, focal adhesion, Golgi apparatus, late endosome, microtubule organizing center, mitochondrion, mitotic spindle, nucleoplasm, nucleus, plasma membrane |
Calculated MW: | 36kDa/41kDa/38kDa/40kDa/43kDa |
Observed MW: | 44kDa |
MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets.
Purification Method: | Affinity purification |
Gene ID: | 5594/5595 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |