The MAP9 Polyclonal Antibody (PAC022415) is an essential tool for researchers studying MAP9, a protein with diverse functions in cellular processes such as microtubule organization and intracellular transport. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the MAP9 protein, this antibody enables accurate detection and analysis in various cell types, making it an invaluable resource for investigations in cell biology and neurology research.MAP9, also known as microtubule-associated protein 9, is involved in critical cellular functions such as cell division and organelle transport.
Its role in regulating microtubule dynamics makes it a key player in processes like mitosis and intracellular trafficking. Research on MAP9 is essential for understanding its implications in neurodegenerative diseases, cancer progression, and other disorders related to microtubule dysfunction. By using the MAP9 Polyclonal Antibody, scientists can further explore the intricacies of MAP9's functions and its potential as a therapeutic target in various pathological conditions.
Antibody Name:
MAP9 Antibody (PACO22415)
Antibody SKU:
PACO22415
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human
Immunogen:
Synthesized peptide derived from internal of human MAP9.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from HuvEc cell, using MAP9 antibody.
Background:
Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing interphase microtubules.
Synonyms:
Microtubule-associated protein 9; Aster-associated protein; ASAP;
UniProt Protein Function:
MAP9: Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing interphase microtubules. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:
Protein type:Cell cycle regulation
Chromosomal Location of Human Ortholog: 4q32.1
Cellular Component: astral microtubule
Biological Process: cytokinesis; regulation of mitosis
NCBI Summary:
ASAP is a microtubule-associated protein required for spindle function, mitotic progression, and cytokinesis (Saffin et al., 2005 [PubMed 16049101]).[supplied by OMIM, Mar 2008]
