The MAP4K3 Polyclonal Antibody (CAB7351) is a valuable tool for researchers studying the MAP4K3 protein, a key regulator of cell signaling pathways involved in inflammation and immune responses. This antibody, produced in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications.MAP4K3, a member of the mitogen-activated protein kinase kinase kinase kinase (MAP4K) family, is known to play a critical role in regulating various cellular processes, including cell proliferation, migration, and survival.
By targeting MAP4K3 with this antibody, researchers can effectively detect and analyze the protein in different cell types, offering insights into its function and potential as a therapeutic target.The antibody's ability to specifically bind to MAP4K3 makes it an ideal tool for studies in immunology, inflammation, and cancer research. Understanding the mechanisms by which MAP4K3 influences cellular pathways can lead to the development of novel therapeutic strategies for diseases characterized by dysregulated immune responses and inflammation.
Product Name:
MAP4K3 Rabbit Polyclonal Antibody
SKU:
CAB7351
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 755-894 of human MAP4K3 (NP_003609.2).
This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
8491
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MAP4K3 antibody (CAB7351) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
