MAP4K2 Rabbit Polyclonal Antibody (CAB17524)
- SKU:
- CAB17524
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | MAP4K2 Rabbit Polyclonal Antibody |
SKU: | CAB17524 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 551-820 of human MAP4K2 (NP_004570.2). |
Sequence: | WAHD LPGL FEQR RLQQ QVPL SIPT NRLT QRII PRRF ALST KIPD TKGC LQCR VVRN PYTG ATFL LAAL PTSL LLLQ WYEP LQKF LLLK NFSS PLPS PAGM LEPL VLDG KELP QVCV GAEG PEGP GCRV LFHV LPLE AGLT PDIL IPPE GIPG SAQQ VIQV DRDT ILVS FERC VRIV NMQG EPTA TLAP ELTF DFPI ETVV CLQD SVLA FWSH GMQG RSLD TNEV TQEI TDET RIFR VLGA HRDI ILES IPTD NPEA HSNL YILT GHQS TY |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | GCK; BL44; RAB8IP; MAP4K2 |
Positive Sample: | U-87MG,A-549,C6,Raji,HeLa,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | basolateral plasma membrane, cytoplasm |
Calculated MW: | 92kDa |
Observed MW: | 110kDa |
The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 5871 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |