The MAP3K9 Polyclonal Antibody (PACO04334) is a valuable tool for researchers studying MAP3K9, a key protein involved in cell signaling pathways. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the MAP3K9 protein, this antibody allows for the detection and analysis of MAP3K9 in a variety of cell types, making it ideal for investigations in molecular biology and cancer research.MAP3K9, also known as Mitogen-Activated Protein Kinase Kinase Kinase 9, plays a crucial role in mediating cellular responses to external stimuli, including growth factors and environmental stressors.
Its involvement in signaling cascades regulating cell growth, differentiation, and survival underscores its importance in processes like tumor development and progression. Furthermore, dysregulation of MAP3K9 has been implicated in a variety of diseases, making it a promising target for therapeutic interventions.By utilizing the MAP3K9 Polyclonal Antibody, researchers can gain insight into the function and regulation of this critical protein, paving the way for advancements in drug discovery and treatment strategies aimed at targeting MAP3K9-mediated pathways in disease settings.
Antibody Name:
MAP3K9 Antibody
Antibody SKU:
PACO04334
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
IHC:1:100-1:300
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the Internal region of human MLK1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
MLK1: a TKL kinase of the MLK family. A dual leucine zipper kinase. Expressed in neuronal cells and may act between Rac1/Cdc42 and MKK4 and -7 in death signaling. Protein type: Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.25; Protein kinase, TKL; TKL group; MLK family; MLK subfamilyChromosomal Location of Human Ortholog: 14q24.2Molecular Function: JUN kinase kinase kinase activity; protein binding; protein homodimerization activity; protein serine/threonine kinase activityBiological Process: activation of JNK activity; protein amino acid autophosphorylation; protein amino acid phosphorylation
